Moderna, Inc.

Moderna did about $1.9B–$2.0B in annual revenue and still ran a deeply negative operating margin (~losses vs sales, not a normal positive margin %).

If you own MRNA, you need to know whether sales keep shrinking or the pipeline starts paying back.

mrna

healthcare large cap updated feb 27, 2026
$42.23
market cap ~$16B · 52-week range $22–$55
xvary composite: 20 / 100 · weak
our overall rating — combines growth, value, risk, and momentum
Start here if you're new
what it is
Moderna makes vaccines and medicines using messenger RNA, the genetic message cells use to build proteins.
how it gets paid
Last year Moderna made about $1.94B in revenue (per recent results commentary on this page).
why growth slowed
Revenue fell ~40% vs. prior year at the annual level. EPS losses were about $2.11 in the latest quarter and $7.26 for the full year (GAAP lines vary by source— verify the filing).
what just happened
Latest quarter revenue was about $678M (down sharply vs. prior year)— not the same as the ~$1.94B full year.
At a glance
C++ balance sheet — some cracks in the foundation
5/100 earnings predictability — expect surprises
return on capital — reconcile with operating losses; screen can lag reality
xvary composite: 20/100 — weak
-$4.75 fy2027 eps est
What they do
Moderna makes vaccines and medicines using messenger RNA, the genetic message cells use to build proteins.
Moderna's moat is the platform, not one drug. On this snapshot the commercial line is still heavily concentrated in covid-era vaccine revenue; RSV and other shots contribute but the mix shifts quarter to quarter. You are buying one research engine with multiple shots on goal— execution still dominates the P&L.
healthcare large-cap biotech vaccines mrna
How they make money
~$1.94B annual revenue · revenue declined ~40% vs. prior year
total revenue
~$1.94B
~40%
The products that matter
commercial covid-19 vaccine
Spikevax
dominant share of ~$1.94B revenue
Covid vaccine sales still anchor the reported top line; other approved products add but do not yet re-rate the model. When demand for the core franchise slips, the whole income statement feels it.
core franchise
pre-revenue pipeline
clinical pipeline
$0 disclosed revenue here
this is where the upside lives, but this snapshot gives you no commercial revenue beyond Spikevax. That means the pipeline is still promise, not proof.
optionality
platform manufacturing base
mRNA platform
$16B market cap backing it
the market is still assigning value beyond the current $1.9B revenue base. Your bet is that the platform eventually earns that trust with more than one product.
second act needed
Key numbers
~$1.94B
annual revenue
You are paying a ~$16B market cap for under $2B of sales. That is a high sales multiple on a shrinking covid-era base.
~-158%
operating margin (loss)
Screen math can show a huge negative “margin %” when revenue shrinks but operating spend stays heavy— read it as operating loss, not a positive ratio.
$590M
long-term debt
Debt is only $590M, or 3% of capital. The bigger issue is that the business still has to earn its keep.
$35
18-month target
The target sits below the current $42.23 price. That means the market is already paying ahead of the analyst view.
Financial health
C++
strength
  • balance sheet grade C++ — below average — limited financial resources
  • risk rank 5 — safer than 5% of stocks
  • price stability 5 / 100
  • long-term debt $590M (3% of capital)
  • net profit margin deeply negative on recent GAAP results— ignore stale positive screen prints
  • return on equity negative in loss years— reconcile any positive screen ROE with filings
C++ — balance sheet is strained by the post-covid burn; do not trust “healthy margin” screens while EPS is negative.
Total return vs. market

You invested $10,000 in MRNA 3 years ago → it's now worth $2,460.

The index would have given you $13,880.

source: institutional data · total return
What just happened
missed estimates
Moderna's latest quarter was about $678M in revenue (down vs. prior year), while EPS stayed deeply negative.
Company commentary on this page cites about $678M for a recent quarter and ~$1.94B for the year, with revenue down ~30% quarter-to-quarter and ~40% year-on-year versus peak demand. EDGAR vs Yahoo EPS can differ (-$5.15 vs about -$2.11)— always match GAAP vs adjusted and the exact period.
~$678M
quarter revenue (approx.)
~-$2.11
quarter EPS (consensus trail)
down vs. prior year
quarter revenue trend
the number that mattered
The ~40% full-year revenue decline to ~$1.94B matters more than any single noisy quarter— demand for the legacy franchise is still rolling down from the pandemic peak.
source: company earnings report, 2026

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What could go wrong

Moderna's biggest risk is simple: it stays a one-product company for longer than the market is willing to tolerate.

med
Spikevax concentration
This snapshot assigns 100% of the company's $1.9B revenue to Spikevax. If demand weakens, there is no second commercial engine here to soften the hit.
Impact: all current revenue is exposed to the performance of one product.
med
pipeline delay or failure
The bull case needs another asset to matter financially. Right now, this page shows no disclosed commercial revenue beyond Spikevax, so any regulatory or clinical delay extends the same concentration problem.
Impact: the company stays dependent on one franchise while the stock keeps pricing future programs.
med
negative earnings persist
FY2026 EPS is estimated at -$6.50 even with revenue expected near $2B. In plain English: a little more sales do not automatically fix the P&L.
Impact: modest revenue growth can still leave you with a business that burns through investor patience.
med
another violent rerating
The short-term outlook sits in the bottom 5%, price stability is 5/100, and a three-year $10,000 investment fell to $2,460. This stock has already shown you what a lost narrative looks like.
Impact: sentiment can keep doing damage even when the science story stays intact.
Combined, these risks leave 100% of current revenue tied to Spikevax while the company is still expected to lose $6.50 per share in FY2026.
source: institutional data · regulatory filings · risk analysis
Pay attention to
calendar
next earnings update
You need to see whether revenue diversification starts showing up in the numbers. Last full review: updated feb 27, 2026.
metric
Spikevax revenue share
Right now it is 100% of the $1.9B revenue line. If that percentage stays pinned near all of it, the second-act argument stays theoretical.
risk
FY2026 loss profile
The -$6.50 EPS estimate matters because it tells you the business is still not translating revenue into profit. Watch whether losses narrow meaningfully.
trend
institutional flow
258 buyers versus 314 sellers in 3q2025 is not subtle. If that trend keeps leaning negative, the wait for pipeline proof gets harder.
Analyst rankings
short-term outlook
bottom 5%
momentum score 5 — in human-speak, analysts expect this stock to lag almost everything else in the near term.
risk profile
high risk
stability score 5 — real risk of large drawdowns, which matches the stock's three-year damage.
chart momentum
average
technical score 3 — the chart is not sending a rescue signal. It is just existing.
earnings predictability
5 / 100
earnings predictability this low means the numbers are hard to model. For you, that means wider outcomes and more surprise risk.
source: institutional data
Institutional activity

258 buyers vs. 314 sellers in 3q2025. total institutional holdings: 0.3B shares.

source: institutional data
Price targets
3-5 year target range
$14 $56
$42 current price
$35 target midpoint · 17% from current · 3-5yr high: $55 (+30% · 7% ann'l return)
source: institutional data · analyst targets

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